First and Main Building
100 SW Main Street, Floor 2
Portland, OR 97204
100 SW Main St FL 2
Portland , OR 97204
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The Portland VA Regional Office is located in the First and Main Building at 100 S.W. Main between Madison and Main Streets. The VA Regional Office is located on the second floor. The main entrance is on the corner of S.W. First Avenue and S.W. Main Street. The First and Main building parking garage can be accessed from SW 2nd Avenue; however, this lot is often full and may be more expensive than other nearby options. There is metered curbside parking throughout the area, as well as a convenient high-rise parking garage one block south of the First and Main building—entry is from SW Jefferson Street. The VA Toll-Free number is: (800) 827-1000 - TDD (800) 829-4833.
Follow the signs to the City of Portland. Take Exit 300, stay in the right lane, follow signs for OMSI/Central Eastside Industrial District. Turn right at SE Water Avenue. Turn right at SE Hawthorne Boulevard, take a slight left at SE Madison Street. Continue onto SE Hawthorne Boulevard/SW Hawthorne Bridge, this will drop you onto the Hawthorne Bridge. You will come off the bridge right in front of the left corner of the First and Main Building.
Follow signs to Portland City Center stay in the right lane take Exit 300B toward US-26 E/OR-99E/OMSI/Oregon City. Keep right at the fork and follow the signs for Morrison St/City Center and merge onto SE Morrison Bridge. Take the ramp to Naito Parkway S/I-5 S, merge onto Naito Parkway, turn right at SW Taylor Street. Take the first left onto SW First Avenue. Turn right at SW Main Street. The First and Main Building will be on your left.
Stay in left lane and take I-5 City Center exit then move into right lane and go over Morrison Bridge. Take the ramp to Naito Pkwy S/I-5 S, merge onto SW Naito Parkway. Turn right at SW Taylor Street. Take the first left onto SW First Avenue. Turn right at SW Main Street. The First and Main Building will be on your left.
Follow signs to Portland City Center. Stay in the center lane this will drop you onto Market Street. Stay on Market Street for 11 blocks to S.W. 2nd. Stay on S.W. 2nd for six blocks to Salmon Street. Turn right on Salmon Street, travel 1 block and turn right onto First Avenue. Turn right at SW Main Street. The First and Main Building will be on your left.
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